Articlegreen2010

The use of PROMIS and assessment center to deliver patient-reported outcome measures in clinical research.

Richard C Gershon · Nan E. Rothrock · Rachel T. Hanrahan · Michael Bass · David F Cella

268 citations0/0 files storedPubMed

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Psychometric Methodologies and Testing Health Systems, Economic Evaluations, Quality of Life Health Education and Validation

Abstract

The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed as one of the first projects funded by the NIH Roadmap for Medical Research Initiative to re-engineer the clinical research enterprise. The primary goal of PROMIS is to build item banks and short forms that measure key health outcome domains that are manifested in a variety of chronic diseases which could be used as a "common currency" across research projects. To date, item banks, short forms and computerized adaptive tests (CAT) have been developed for 13 domains with relevance to pediatric and adult subjects. To enable easy delivery of these new instruments, PROMIS built a web-based resource (Assessment Center) for administering CATs and other self-report data, tracking item and instrument development, monitoring accrual, managing data, and storing statistical analysis results. Assessment Center can also be used to deliver custom researcher developed content, and has numerous features that support both simple and complicated accrual designs (branching, multiple arms, multiple time points, etc.). This paper provides an overview of the development of the PROMIS item banks and details Assessment Center functionality.

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References

2010The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008 2007Psychometric Evaluation and Calibration of Health-Related Quality of Life Item Banks 2007Evaluation of Item Candidates 2007The future of outcomes measurement: item banking, tailored short-forms, and computerized adaptive assessment 2010An item response analysis of the pediatric PROMIS anxiety and depressive symptoms scales 2010Assessment of neurological and behavioural function: the NIH Toolbox

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