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Lost in translation: preclinical studies on 3,4‐methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans
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Lost in translation: preclinical studies on 3,4‐methylenedioxymethamphetamine provide information on mechanisms of action, but do not allow accurate prediction of adverse events in humans (2011)Lost in translation: preclinical studies …The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study (2010)The safety and efficacy of ±3…Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview (2009)Molecular and Cellular Mechan…The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents* (2006)The origin of MDMA (ecstasy) …The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003)The Pharmacology and Clinical…The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats (2002)The pharmacology of the acute…3,4-Methylenedioxymethamphetamine (Ecstasy) and Alcohol Interactions in Humans: Psychomotor Performance, Subjective Effects, and Pharmacokinetics (2002)3,4-Methylenedioxymethampheta…3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose (2001)3,4-Methylenedioxymethampheta…Cardiovascular and Neuroendocrine Effects and Pharmacokinetics of 3,4-Methylenedioxymethamphetamine in Humans (1999)Cardiovascular and Neuroendoc…The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy') (1998)The relationship between the …Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers (1998)Psychological and Cardiovascu…An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine. (1998)An integrated hypothesis for …Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations (1995)Psychobiologic effects of 3,4…The Psychological and Physiological Effects of MDMA on Normal Volunteers (1986)The Psychological and Physiol…Subjective Reports of the Effects of MDMA in a Clinical Setting (1986)Subjective Reports of the Eff…Can Drugs Be Used to Enhance the Psychotherapeutic Process? (1986)Can Drugs Be Used to Enhance …Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals (1985)Hallucinogenic Amphetamine Se…Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings (1998)Psychological and Physiological Effects of MDMA (“Ecstasy”) after Pretreatment with the 5-HT2 Antagonist Ketanserin in Healthy Humans (2000)Gender differences in the subjective effects of MDMA (2001)3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings (2006)3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. (1987)In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain (1987)MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons (1988)The relative contributions of ecstasy and cannabis to cognitive impairment (2000)Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy (2005)Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. (1987)Hallucinogens (2004)Residual neurocognitive features of long‐term ecstasy users with minimal exposure to other drugs (2010)In Vivo Imaging of Cerebral Serotonin Transporter and Serotonin2A Receptor Binding in 3,4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) and Hallucinogen Users (2011)3,4-methylenedioxymethamphetamine (MDMA): current perspectives (2013)Emotional processing of fear: Exposure to corrective information. (1986)Combat Duty in Iraq and Afghanistan, Mental Health Problems, and Barriers to Care (2004)Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication (2005)Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology (2014)Treating PTSD: A Review of Evidence-Based Psychotherapy Interventions (2018)Psychedelics and Psychedelic-Assisted Psychotherapy (2020)Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens (1986)Positron Emission Tomography and Fluorodeoxyglucose Studies of Metabolic Hyperfrontality and Psychopathology in the Psilocybin Model of Psychosis (1997)A randomized, controlled pilot study of MDMA (±3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD) (2012)Effects of enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices (1986)The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA) (2003)A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response (2004)Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug (1992)Ecstasy (MDMA): a review of its possible persistent psychological effects (2000)Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study (2012)Incidence of Recreational Use of 3,4-Methylenedimethoxymethamphetamine (MDMA, Ecstasy) on an Undergraduate Campus (1987)Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms (2003)A review of the acute subjective effects of MDMA/ecstasy (2006)Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. (1988)Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research (2001)Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity (2002)Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana (2008)The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers (2014)
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References

  • 2003The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)1,271 cited
  • 2010The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study673 cited
  • 1998Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers448 cited
  • 1986Subjective Reports of the Effects of MDMA in a Clinical Setting413 cited
  • 1985Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals367 cited
  • 1999Cardiovascular and Neuroendocrine Effects and Pharmacokinetics of 3,4-Methylenedioxymethamphetamine in Humans362 cited
  • 2009Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview291 cited
  • 1998The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy')242 cited
  • 1986The Psychological and Physiological Effects of MDMA on Normal Volunteers226 cited
  • 2002The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats221 cited
  • 2006The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents*198 cited
  • 20023,4-Methylenedioxymethamphetamine (Ecstasy) and Alcohol Interactions in Humans: Psychomotor Performance, Subjective Effects, and Pharmacokinetics191 cited

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  • 1986Can Drugs Be Used to Enhance the Psychotherapeutic Process?187 cited
  • 20013,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose185 cited
  • 1998An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine.181 cited
  • 1995Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations175 cited
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