CIRCADIAN VARIATIONS IN PERFORMANCE, PSYCHOLOGICAL RATINGS, CATECHOLAMINE EXCRETION AND URINE FLOW DURING PROLONGED SLEEP DEPRIVATION

Jan E. Fröberg · Claes-Göran Karlsson · L. David Levi · L Lidberg

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Sleep and Work-Related Fatigue Circadian rhythm and melatonin Sleep and Wakefulness Research

Abstract

The paper presents two experiments, in which a total of 63 subjects were deprived of sleep for 75 hours with simultaneous 3-hourly measurements of physiological variables (e.g. catecholamine excretion), self-ratings, and performance. The purpose of the experiments was to study: (a) circadian rhythms in a number of biochemical and psychological variables under controlled conditions. (b) changes in these variables with the duration of sleep deprivation. (c) temporal interrelationships between the biochemical and psychological variables. In all the above respects, the first experiment was an exploratory study, the results being further tested in the second.

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