Proteomic Profiling of the Photo‐Oxidation of Silk Fibroin: Implications for Historic Tin‐Weighted Silk

Caroline Solazzo · Jolon M. Dyer · Santanu Deb‐Choudhury · Stefan Clerens · Paul Wyeth

36 citations0/0 files storedPhotochemistry and Photobiology

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Cultural Heritage Materials Analysis Dyeing and Modifying Textile Fibers Silk-based biomaterials and applications

Abstract

The stability of silk proteins to ultraviolet light is an issue of significant concern in both the appearance retention of silk-derived products and the preservation of historic silk textiles. Until now, evaluation of silk degradation has only been performed at the holistic, rather than molecular level. This article describes the first proteomic profiling of silk photo-oxidation, characterizing protein primary level modification leading to coloration changes, and evaluating the effects of tin weighting on photodegradation. Heavy-chain fibroin, the main proteinaceous component of the silk thread, is a repetitive, highly crystalline protein with a content rich in tyrosine. Photoproducts of tyrosine were characterized and the levels of oxidative modification at the protein primary structural level correlated with changes in coloration and tensile strength. The effect of tin as a weighting agent used on historical fabrics was examined. Tin-weighted fabrics were evaluated following two treatments (pink and dynamite) and proteomic analysis revealed a significant increase in oxidatively modified amino acid residues within the pink-treated silk. These findings offer new insight into the molecular-level oxidation of silk proteins under UV exposure, and the effects of silk treatments in either exacerbating or ameliorating this degradation.

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References

2011Heat and moisture promoted deterioration of raw silk estimated by amino acid analysis 2007Crystallinity and degradation of silk: correlations between analytical signatures and physical condition on ageing 2005Characterization of Historic Silk by Polarized Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy for Informed Conservation 1989Degradation in Weighted and Unweighted Historic Silks

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