No open-access location is known for this record yet.
No open-access location is known for this record yet.
This chapter presents the construction of multivariate control charts with the multivariate data. Multivariate statistical process control (MSPC) requires applications of methods and tools of multivariate data analysis, and the first section of the chapter reviews such methods and tools. A section focuses on multivariate data and describes several multivariate process capability indices. In setting MSPC charts, one meets several alternative scenarios, such as internally derived targets and externally assigned targets, derived from the characteristics of the reference sample and the appropriate control procedure. The final section deals with tolerance specifications, where a special application of MSPC to the monitoring of bioequivalence of drug product dissolution profiles, is explained. In this application, tablets manufactured by a generic drug company are compared to the original product at several dissolution times. Controlled Vocabulary Terms Mahalanobis distance; multivariate control charts; multivariate statistics; statistical process control
Loading…
Imported from OpenAlex (CC0) — nothing here is generated.