Levels of childhood vaccination coverage and the impact of maternal HIV status on child vaccination status in rural KwaZulu‐Natal, South Africa*

James Ndirangu · Till Bärnighausen · Frank Courteney Tanser · Khin San Tint · Marie‐Louise Newell

79 citations0/0 files storedTropical Medicine & International Health

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Vaccine Coverage and Hesitancy HIV/AIDS Research and Interventions Global Maternal and Child Health

Abstract

OBJECTIVES: To analyse coverage of childhood vaccinations in a rural South African population and investigate whether maternal HIV status is associated with children's vaccination status. METHODS: 2 431 children with complete information, 12-23 months of age at some point during the period January 2005 through December 2006 and resident in the Africa Centre Demographic Surveillance Area at the time of their birth were investigated. We examined the relationship between maternal HIV status and child vaccination status for five vaccinations [Bacillus Calmette-Guérin (BCG), diphtheria-tetanus-pertussis (DTP3), poliomyelitis (polio3), hepatitis B (HepB3), and measles] in multiple logistic regressions, controlling for household wealth, maternal age, maternal education and distances to roads, fixed and mobile clinics. RESULTS: Coverage of the five vaccinations ranged from 89.3% (95% CI 81.7-93.9) for BCG to 77.3% (67.1-83.6) for measles. Multivariably, maternal HIV-positive status was significantly associated with lower adjusted odds ratios (AOR) of child vaccination for all vaccines [(AOR) 0.60-0.74, all P < or = 0.036] except measles (0.75, P = 0.073), distance to mobile clinic was negatively associated with vaccination status (all P < or = 0.029), household wealth was positively (all P < or = 0.013) and distance to nearest road negatively (all P < or = 0.004) associated with vaccination status. CONCLUSION: Positive maternal HIV status independently reduces children's probability to receive child vaccinations, which likely contributes to the morbidity and mortality differential between children of HIV-positive and HIV-negative mothers. As a means of increasing vaccination coverage, policy makers should consider increasing the number of mobile clinics in this and similar communities in rural Africa.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 79 citations exist upstream.

References

2004Applied Spatial Statistics for Public Health Data 1979Education as a Factor in Mortality Decline An Examination of Nigerian Data 2006Modelling and understanding primary health care accessibility and utilization in rural South Africa: An exploration using a geographical information system 2008Tracking progress towards universal childhood immunisation and the impact of global initiatives: a systematic analysis of three-dose diphtheria, tetanus, and pertussis immunisation coverage 2007Health workers and vaccination coverage in developing countries: an econometric analysis 2003Analysing the primacy of distance in the utilization of health services in the Ahafo‐Ano South district, Ghana 2003Validity of reported vaccination coverage in 45 countries 1998The effect of distance from home on attendance at a small rural health centre in Papua New Guinea

Cited by

2010Rethinking the benefits and costs of childhood vaccination: The example of the Haemophilus influenzae type b vaccine☆2014Social inequalities in vaccination uptake among children aged 0–59 months living in Madagascar: An analysis of Demographic and Health Survey data from 2008 to 2009 2015The causal effect of childhood measles vaccination on educational attainment: A mother fixed-effects study in rural South Africa

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.