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The Neurobiology of Violence

181 citations0/0 files storedJournal of Neuropsychiatry

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Psychopathy, Forensic Psychiatry, Sexual Offending Neurotransmitter Receptor Influence on Behavior Neural and Behavioral Psychology Studies

Abstract

Clinical correlates of violent behavior are known, but the underlying mechanisms are not well understood. This article reviews recent progress in the understanding of such mechanisms involving complex interactions between genes, prenatal and perinatal environmental factors, and rearing conditions. Violent behavior is heterogeneous; that is, impulsive and premeditated violent acts differ in their origins, mechanisms, and management. Recent molecular genetic studies of neurotransmitter regulation are providing new insights into pathophysiology of violent behavior. Functional anatomy of neurotransmitters involved in the regulation of violent behavior is being studied with recently developed brain imaging methods. Increasing evidence indicates commonalities between the neurobiology of violent and suicidal behavior. Progress in the prevention and management of violent behavior depends on studies that address biological factors in their social context. This article updates a previous review.

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References

19765-HIAA in the Cerebrospinal Fluid 1998Violence by People Discharged From Acute Psychiatric Inpatient Facilities and by Others in the Same Neighborhoods 1998A New Intellectual Framework for Psychiatry 1998Violence and Severe Mental Illness: The Effects of Substance Abuse and Nonadherence to Medication 1997Fluoxetine and Impulsive Aggressive Behavior in Personality-Disordered Subjects 1998Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers 1996Mental disorder and crime. Evidence from a Danish birth cohort.1998The neurobiology of suicide

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2010Violence in sleep 2014Neurodevelopmental and psychosocial risk factors in serial killers and mass murderers 2004Violence in the emergency department: A literature review 2004A neuropsychological investigation into violence and mental illness 2001Toward an understanding of violence: neurobehavioral aspects of unwarranted physical aggression: Aspen Neurobehavioral Conference consensus statement.

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