Article1998

Antidepressants in panic disorder: clinical and preclinical mechanisms.

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Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Neurotransmitter Receptor Influence on Behavior Treatment of Major Depression

Abstract

Advances have been made in understanding the biology of panic disorder and the role of the underlying serotonergic dysfunction. This review summarizes the biological evidence for the involvement of serotonin in the pathogenesis of panic disorder and considers the 2 opposing theories that are currently prevalent (5-HT excess and 5-HT deficit). The serotonin selective reuptake inhibitors are increasingly considered as first-line treatment for panic disorder, and the interaction of these agents with the serotonergic system is considered.

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References

1983Manual for the Child: Behavior Checklist and Revised Child Behavior Profile 1978Normative data on Revised Conners Parent and Teacher Rating Scales 1997Conners' rating scales-revised : technical manual 1983Factor Comparability As A Means Of Determining The Number Of Factors And Their Rotation

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2010Laboratory stressors in clinically anxious and non-anxious individuals: The moderating role of mindfulness 2009Current Considerations in the Treatment of Generalized Anxiety Disorder 2005Serotonin Function in Panic Disorder: Important, But Why?2014Oppositional Defiant Disorder Is Better Conceptualized as a Disorder of Emotional Regulation 2000Effects of tryptophan depletion on carbon dioxide provoked panic in panic disorder patients 2009A Tryptophan Hydroxylase 2 Gene Polymorphism is Associated with Panic Disorder 2000Serotonergic drugs in the treatment of depressive and anxiety disorders 2003WCA Recommendations for the Long-Term Treatment of Panic Disorder

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