Mapping the EQ-5D Index from the SF-12: US General Population Preferences in a Nationally Representative Sample

Patrick W. Sullivan · Vahram H. Ghushchyan

249 citations0/0 files storedMedical Decision Making

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Health Systems, Economic Evaluations, Quality of Life Economic and Environmental Valuation Delphi Technique in Research

Abstract

BACKGROUND: Previous mapping algorithms estimating EQ-5D index scores from the SF-12 were based on preferences from a UK community sample. However, preferences based on the general US population are most appropriate for costeffectiveness analyses done from the societal perspective in the United States. OBJECTIVE: To provide a mapping algorithm for estimating EQ-5D index scores from the SF-12 based on a nationally representative sample and using preferences based on the general US population: METHODS: The Medical Expenditure Panel Survey (MEPS) 2002 and 2000 data were used as independent derivation and validation sets to estimate the relationship between SF-12 scores and EQ-5D index scores, controlling for sociodemographic characteristics and comorbidity burden. Prediction equations for end-users who only have access to SF-12 scores were derived and compared. The empirical performance of censored least absolute deviations (CLAD), Tobit, and ordinary least squares (OLS) analytic methods were compared by calculating the mean prediction error in the validation set. RESULTS: The fully specified CLAD model resulted in the lowest mean prediction error, followed by OLS and Tobit. The CLAD prediction equation based only on SF-12 scores performed better than the fully specified OLS and Tobit models. CONCLUSION: The current research provides an algorithm for mapping EQ-5D index scores from the SF-12. This algorithm may provide analysts with an avenue to obtain appropriate preference-based health-related quality-of-life scores for use in cost-effectiveness analyses when only SF-12 data are available.

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2019Theory of games and economic behavior 1990EuroQol - a new facility for the measurement of health-related quality of life 2005Methods for the Economic Evaluation of Health Care Programmes 1983Limited-dependent and qualitative variables in econometrics 1996Cost-Effectiveness in Health and Medicine 1996EuroQol: the current state of play 1997Modeling Valuations for EuroQol Health States 1987Methods for the economic evaluation of health care programmes

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2008Deriving an Algorithm to Convert the Eight Mean SF-36 Dimension Scores into a Mean EQ-5D Preference-Based Score from Published Studies (Where Patient Level Data Are Not Available)2009Mapping SF-36 onto the EQ-5D index: how reliable is the relationship?2009Mapping the Modified Rankin Scale (mRS) Measurement into the Generic EuroQol (EQ-5D) Health Outcome 2007Comparing the Incomparable? A Systematic Review of Competing Techniques for Converting Descriptive Measures of Health Status into QALY-Weights 2009Predicting EuroQol (EQ-5D) scores from the patient-reported outcomes measurement information system (PROMIS) global items and domain item banks in a United States sample

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