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Ideally, patients with mild tics who have made a good adaptation in their lives can avoid the use of medications. Educating patients, family members, peers, and school personnel regarding the nature of Tourette syndrome (TS), restructuring the school environment, and providing supportive counseling are measures that may be sufficient to avoid pharmacotherapy. Medication therapy should be considered if tics are functionally disabling and not remediable to nonpharmacologic interventions. A variety of therapeutic agents are now available to treat tics, and each medication should be chosen on the basis of expected efficacy and potential side effects. Dosages should be titrated slowly to achieve the lowest satisfactory dosage that is sufficient to attain a tolerable level of symptoms.
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