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The cost of drug development: A systematic review
5 references·16 citing·35 second hop
The cost of drug development: A systematic review (2011)The cost of drug development: A systemati…How to improve R&D productivity: the pharmaceutical industry's grand challenge (2010)How to improve R&D productivi…The cost of biopharmaceutical R&D: is biotech different? (2007)The cost of biopharmaceutical…Estimating The Cost Of New Drug Development: Is It Really $802 Million? (2006)Estimating The Cost Of New Dr…The price of innovation: new estimates of drug development costs (2003)The price of innovation: new …Cost of innovation in the pharmaceutical industry (1991)Cost of innovation in the pha…A hybrid multi‐criteria decision‐making approach to evaluate interrelationships and impacts of supply chain performance factors on pharmaceutical industry (2022)A hybrid multi‐criteria decis…Towards Pharma 4.0 in clinical trials: A future-orientated perspective (2021)Towards Pharma 4.0 in clinica…R&D Costs of New Medicines: A Landscape Analysis (2021)R&D Costs of New Medicines: A…Money Don't matter? How incubation experience affects start-up entrepreneurs' resource valuation (2021)Money Don't matter? How incub…How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment (2021)How Much Does It Cost to Rese…Pricing of pharmaceuticals is becoming a major challenge for health systems (2020)Pricing of pharmaceuticals is…Gimme shelter? Heterogeneous preferences for tangible and intangible resources when choosing an incubator (2019)Gimme shelter? Heterogeneous …Pathways to ensure universal and affordable access to hepatitis C treatment (2018)Pathways to ensure universal …Forecasting of emerging therapeutic monoclonal antibodies patents based on a decision model (2018)Forecasting of emerging thera…Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study (2018)Estimating the cost of vaccin…Effects of price cap regulation on the pharmaceutical supply chain (2018)Effects of price cap regulati…Is Open Science the Future of Drug Development? (2017)Is Open Science the Future of…Key cost drivers of pharmaceutical clinical trials in the United States (2016)Key cost drivers of pharmaceu…Incremental cost per quality-adjusted life year gained? The need for alternative methods to evaluate medical interventions for ultra-rare disorders (2014)Incremental cost per quality-…How Drugs are Developed and Approved by the FDA: Current Process and Future Directions (2014)How Drugs are Developed and A…Quality of life instruments for economic evaluations in health and social care for older people: A systematic review (2013)Quality of life instruments f…Principles of Corporate Finance. 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(2004)Diagnosing the decline in pharmaceutical R&D efficiency (2012)Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018 (2020)The Human Right to Health (2011)Innovation in the pharmaceutical industry: New estimates of R&D costs (2016)Vaccines and global health: In search of a sustainable model for vaccine development and delivery (2019)Toward a New Common Sense (2021)Defining the hidden evidence in autism research. Forty per cent of rigorously designed clinical trials remain unpublished ‐ a cross‐sectional analysis (2016)Addressing the challenge of high-priced prescription drugs in the era of precision medicine: A systematic review of drug life cycles, therapeutic drug markets and regulatory frameworks (2017)The Future Role of the United States in Global Health (2017)Clinical development success rates for investigational drugs (2014)Estimated Costs of Pivotal Trials for Novel Therapeutic Agents Approved by the US Food and Drug Administration, 2015-2016 (2018)Examining the Use of Real‐World Evidence in the Regulatory Process (2019)Disruption of healthcare: Will the COVID pandemic worsen non-COVID outcomes and disease outbreaks? (2020)Analysis of pharma R&D productivity – a new perspective needed (2023)Costs of Drug Development and Research and Development Intensity in the US, 2000-2018 (2024)
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References

  • 2003The price of innovation: new estimates of drug development costs4,264 cited
  • 2010How to improve R&D productivity: the pharmaceutical industry's grand challenge3,562 cited
  • 2006Estimating The Cost Of New Drug Development: Is It Really $802 Million?906 cited
  • 1991Cost of innovation in the pharmaceutical industry763 cited
  • 2007The cost of biopharmaceutical R&D: is biotech different?517 cited

Cited by

  • 2016Key cost drivers of pharmaceutical clinical trials in the United States401 cited
  • 2021How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment360 cited
  • 2018Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study281 cited
  • 2013Quality of life instruments for economic evaluations in health and social care for older people: A systematic review194 cited
  • 2014How Drugs are Developed and Approved by the FDA: Current Process and Future Directions162 cited
  • 2020Pricing of pharmaceuticals is becoming a major challenge for health systems145 cited
  • 2021R&D Costs of New Medicines: A Landscape Analysis87 cited
  • 2018Pathways to ensure universal and affordable access to hepatitis C treatment76 cited
  • 2014Incremental cost per quality-adjusted life year gained? The need for alternative methods to evaluate medical interventions for ultra-rare disorders

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73 cited
  • 2018Effects of price cap regulation on the pharmaceutical supply chain66 cited
  • 2021Money Don't matter? How incubation experience affects start-up entrepreneurs' resource valuation63 cited
  • 2019Gimme shelter? Heterogeneous preferences for tangible and intangible resources when choosing an incubator56 cited
  • 2018Forecasting of emerging therapeutic monoclonal antibodies patents based on a decision model40 cited
  • 2022A hybrid multi‐criteria decision‐making approach to evaluate interrelationships and impacts of supply chain performance factors on pharmaceutical industry40 cited
  • 2017Is Open Science the Future of Drug Development?27 cited
  • 2021Towards Pharma 4.0 in clinical trials: A future-orientated perspective26 cited