Olanzapine in the treatment‐resistant, combat‐related PTSD – a series of case reports

Miro Jakovljević · Marina Šagud · Alma Mihaljević-Peleš

69 citations0/0 files storedActa Psychiatrica Scandinavica

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Posttraumatic Stress Disorder Research Psychoanalysis and Psychopathology Research Sleep and related disorders

Abstract

OBJECTIVE: Nightmares and insomnia in combat-related post-traumatic stress disorder (PTSD) might be resistant to treatment with selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines. METHOD: We describe five case reports of patients suffering from long-lasting and intractable nightmares and insomnia. They were given different psychotropic agents in past few years, with no improvement in their sleep disturbance. Olanzapine was added to the current treatment regimen. RESULTS: Both nightmares and insomnia improved rapidly after olanzapine institution in all of five patients. No adverse events of olanzapine were reported. CONCLUSION: Olanzapine augmentation might be useful in alleviating treatment-resistant nightmares and insomnia in patients with combat-related PTSD.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 69 citations exist upstream.

References

2000Efficacy and Safety of Sertraline Treatment of Posttraumatic Stress Disorder 2001Multicenter, Double-blind Comparison of Sertraline and Placebo in the Treatment of Posttraumatic Stress Disorder 2001Olanzapine in the treatment of post-traumatic stress disorder: a pilot study 2001Post‐traumatic stress disorder: a review of psychobiology and pharmacotherapy 2000Selective serotonin reuptake inhibitors in the treatment of post-traumatic stress disorder: a metaanalysis of randomized controlled trials

Cited by

2018Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery 2005Quetiapine as an adjunctive treatment for post-traumatic stress disorder: an 8-week open-label study 2018Management of Post-Traumatic Nightmares: a Review of Pharmacologic and Nonpharmacologic Treatments Since 2013

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.