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Staudinger's visions paved the way for the development of modern polymeric materials with very versatile properties and new opportunities at the interface of materials and life sciences. This is confirmed in this Essay, written to mark the 50th anniversary of the award of the Nobel Prize for Chemistry to Hermann Staudinger. His revolutionary concept, which initially attracted heavy opposition, marked the beginning of the new era of rational molecular design of structural and functional polymeric materials, whose property profiles are tailored by varying their molecular architectures.
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