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Treating insomnia: Current and investigational pharmacological approaches

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References

2003The Cumulative Cost of Additional Wakefulness: Dose-Response Effects on Neurobehavioral Functions and Sleep Physiology From Chronic Sleep Restriction and Total Sleep Deprivation3,173 cited
2009Neurocognitive Consequences of Sleep Deprivation2,154 cited
1996Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults1,830 cited
2005Neurocognitive Consequences of Sleep Deprivation1,472 cited
2005Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits1,158 cited
2002Neuropsychopharmacology: The Fifth Generation of Progress1,019 cited
2001Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications884 cited
1997Psychophysiological insomnia: the behavioural model and a neurocognitive perspective795 cited
2004Functional Neuroimaging Evidence for Hyperarousal in Insomnia752 cited
2003Role of Stress, Arousal, and Coping Skills in Primary Insomnia739 cited
1997Prevalence, burden, and treatment of insomnia in primary care694 cited
2003Sustained Efficacy of Eszopiclone Over 6 Months of Nightly Treatment: Results of a Randomized, Double-Blind, Placebo-Controlled Study in Adults with Chronic Insomnia630 cited
1992Circadian and sleep/wake dependent aspects of subjective alertness and cognitive performance602 cited

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2004

Vulnerability to Stress-related Sleep Disturbance and Hyperarousal

468 cited

1999Quality of life in people with insomnia.466 cited

2005An efficacy, safety, and dose–response study of Ramelteon in patients with chronic primary insomnia434 cited

Cited by

2008Sleep, insomnia and falls in elderly patients166 cited
2009Searching for perfect sleep: the continuing evolution of GABA A receptor modulators as hypnotics163 cited
2010Insomnia risks and costs: health, safety, and quality of life.138 cited
2011Next-Day Effects of Ramelteon (8 mg), Zopiclone (7.5 mg), and Placebo on Highway Driving Performance, Memory Functioning, Psychomotor Performance, and Mood in Healthy Adult Subjects137 cited
2011Efficacy and Safety of Doxepin 3 and 6 mg in a 35-day Sleep Laboratory Trial in Adults with Chronic Primary Insomnia129 cited
2008Alertness management strategies for operational contexts110 cited
2014The acute cognitive effects of zopiclone, zolpidem, zaleplon, and eszopiclone: A systematic review and meta-analysis103 cited
2009Highway driving performance and cognitive functioning the morning after bedtime and middle‐of‐the‐night use of gaboxadol, zopiclone and zolpidem101 cited
2013Review of the histamine system and the clinical effects of H1 antagonists: Basis for a new model for understanding the effects of insomnia medications101 cited
2015Randomised clinical trial of the effects of prolonged-release melatonin, temazepam and zolpidem on slow-wave activity during sleep in healthy people81 cited
2008Hypnotic use for insomnia management in chronic obstructive pulmonary disease71 cited
2012Drugs for insomnia70 cited
2013Neuroscience-driven discovery and development of sleep therapeutics63 cited
2010New guidelines for diagnosis and treatment of insomnia51 cited
2008Next‐day cognition, psychomotor function, and driving‐related skills following nighttime administration of eszopiclone51 cited
2016Effectiveness of Benzodiazepine Receptor Agonists in the Treatment of Insomnia: An Examination of Response and Remission Rates49 cited