Use of Computerized Psychomotor Testing in Determining CNS Effects of Drugs

Richard C. Berchou · Robert I. Block

13 citations0/0 files storedPerceptual and Motor Skills

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Psychological Testing and Assessment Traffic and Road Safety Forensic Toxicology and Drug Analysis

Abstract

Two interactive, computer-controlled tests--critical flicker fusion and discriminant reaction time tasks--are described. These tasks, and subjective sedation ratings using visual analogue scales, were shown to be sensitive in a dose-related fashion to the effects of CNS depressants (diazepam, 15 mg and lorazepam, 1 and 2 mg). Such brief, interactive, computerized tasks should be useful in screening new agents for CNS activity in humans.

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1956A continuous performance test of brain damage.1980Techniques in psychophysiology 1978Sensitivity and accuracy of the visual analogue scale: a psycho‐ physical classroom experiment.1960A COMPARISON OF THE EFFECTS OF MEPROBAMATE, PHENOBARBITAL AND d-AMPHETAMINE ON TWO PSYCHOLOGICAL TESTS

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1996The digit vigilance test: reliability, validity, and sensitivity to diazepam

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