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Sir.—Influenza is an important cause of pediatric morbidity, especially in children with chronic cardiopulmonary conditions.1The American Academy of Pediatrics' Committee on Infectious Diseases recommends that children with asthma be targeted for vaccination.2Although pediatricians devote much attention to universal immunizations, only 1% to 7% of high-risk children are vaccinated against influenza.1Mailed reminders have been effective in improving adherence to recommended health care in other settings. Several studies in adult medicine demonstrated that mailed reminders improve the rate of immunization against influenza.3-5Mailed reminders have also been effective in improving compliance with immunizations in pediatric clinics.6We were unable to find any studies addressing the effectiveness of mailed reminders in improving the rate of influenza immunization in pediatric clinics. Accordingly, we performed a controlled clinical trial to answer the following question: do computer-generated reminder letters improve the rate of influenza immunization in children
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