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Health-Related Quality of Life as Measured with EQ-5D among Populations with and without Specific Chronic Conditions: A Population-Based Survey in Shaanxi Province, China

Zhijun Tan · Ying Liang · Siming Liu · Haibo Tu · Ling-Xia Guo · Yongyong Xu

80 citations0/0 files storedPLoS ONE

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Health Systems, Economic Evaluations, Quality of Life Aging, Health, and Disability Chronic Disease Management Strategies

Abstract

INTRODUCTION: The aim of this study was to examine health-related quality of life (HRQoL) as measured by EQ-5D and to investigate the influence of chronic conditions and other risk factors on HRQoL based on a distributed sample located in Shaanxi Province, China. METHODS: A multi-stage stratified cluster sampling method was performed to select subjects. EQ-5D was employed to measure the HRQoL. The likelihood that individuals with selected chronic diseases would report any problem in the EQ-5D dimensions was calculated and tested relative to that of each of the two reference groups. Multivariable linear regression models were used to investigate factors associated with EQ VAS. RESULTS: The most frequently reported problems involved pain/discomfort (8.8%) and anxiety/depression (7.6%). Nearly half of the respondents who reported problems in any of the five dimensions were chronic patients. Higher EQ VAS scores were associated with the male gender, higher level of education, employment, younger age, an urban area of residence, access to free medical service and higher levels of physical activity. Except for anemia, all the selected chronic diseases were indicative of a negative EQ VAS score. The three leading risk factors were cerebrovascular disease, cancer and mental disease. Increases in age, number of chronic conditions and frequency of physical activity were found to have a gradient effect. CONCLUSION: The results of the present work add to the volume of knowledge regarding population health status in this area, apart from the known health status using mortality and morbidity data. Medical, policy, social and individual attention should be given to the management of chronic diseases and improvement of HRQoL. Longitudinal studies must be performed to monitor changes in HRQoL and to permit evaluation of the outcomes of chronic disease intervention programs.

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1992The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.1992The MOS 36-ltem Short-Form Health Survey (SF-36)1996EuroQol: the current state of play 2001EQ-SD: a measure of health status from the EuroQol Group 2005US Valuation of the EQ-5D Health States 1993Health status and health policy: quality of life in health care evaluation and resource allocation 2001The Health Utilities Index (HUI®) system for assessing health-related quality of life in clinical studies 2010A review of health utilities using the EQ-5D in studies of cardiovascular disease

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