Article1985

A DOUBLE‐BLIND DRUG TRIAL OF TREATMENT IN YOUNG CHILDREN WITH WAKING PROBLEMS

99 citations0/0 files storedJournal of Child Psychology and Psychiatry

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Abstract

A double-blind trial using trimeprazine tartrate was carried out in 22 children with severe waking problems. On parental verbal reports sleep was significantly improved on the drug compared with the original baseline and the placebo, but diaries kept by the parents showed that this improvement was clinically only moderate, with many wakeful nights still occurring. Taking the drug produced no permanent effect on sleep patterns and a follow-up of 14 children 6 months later showed persisting sleep problems in the majority.

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References

1981A Community Survey of Characteristics of One- to Two-Year-Olds with Sleep Disruptions 1985BEHAVIOURAL METHODS IN THE TREATMENT OF SLEEP DISORDERS—A PILOT STUDY 1974Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence

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1993Sleep problems in childhood 2008Preschoolers’ sleep behaviour: associations with parental hardiness, sleep‐related cognitions and bedtime interactions 1990Behavioral Treatment of Multiple Childhood Sleep Disorders 2004Reducing Bedtime Disturbance and Night Waking Using Positive Bedtime Routines and Sleep Restriction 2005The use of clonidine for severe and intractable sleep problems in children with neurodevelopmental disorders 2001Sleep Problems in Children with Developmental Disorders 2000Behavioural treatments for sleep problems in children and adolescents with physical illness, psychological problems or intellectual disabilities 2001Classification of Young Children's Sleep Problems: A Pilot Study

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