Review2003

Neuroimaging Studies of Amygdala Function in Anxiety Disorders

Scott L. Rauch · Lisa M. Shin · Christopher I. Wright

463 citations0/0 files storedAnnals of the New York Academy of Sciences

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Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Memory and Neural Mechanisms Neural and Behavioral Psychology Studies

Abstract

Neuroimaging research has helped to advance neurobiological models of anxiety disorders. The amygdala is known to play an important role in normal fear conditioning and is implicated in the pathophysiology of anxiety disorders. The amygdala may also be a target for the beneficial effects of cognitive-behavioral and medication treatments for anxiety disorders. In the current paper, we review neuroimaging research pertaining to the role of the amygdala in anxiety disorders and their treatment. Moreover, we discuss the development of new neuroimaging paradigms for measuring aspects of amygdala function, as well as the function of related brain regions. We conclude that such tools hold great promise for facilitating progress in relevant basic neuroscience as well as clinical research domains.

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References

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Cited by

2006Antidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues 2007Failure of Frontolimbic Inhibitory Function in the Context of Negative Emotion in Borderline Personality Disorder 2008The neural bases of obsessive–compulsive disorder in children and adults 2010Human Bed Nucleus of the Stria Terminalis Indexes Hypervigilant Threat Monitoring

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