How Safe Is Safe Enough? New Infections and the U.S. Blood Supply

Jody S. Heymann · Timothy F. Brewer · Harvey V. Fineberg · Mary Elizabeth Wilson

9 citations0/0 files storedAnnals of Internal Medicine

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Blood donation and transfusion practices HIV/AIDS Research and Interventions Blood transfusion and management

Abstract

Editorial1 October 1992How Safe Is Safe Enough? New Infections and the U.S. Blood SupplyS. Jody Heymann, MD, PhD, Timothy F. Brewer, MD, MPH, Harvey V. Fineberg, MD, PhD, Mary E. Wilson, MDS. Jody Heymann, MD, PhDSearch for more papers by this author, Timothy F. Brewer, MD, MPHSearch for more papers by this author, Harvey V. Fineberg, MD, PhDSearch for more papers by this author, Mary E. Wilson, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-7-612 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecently, 14 patients who were negative for human immunodeficiency virus (HIV) types 1 and 2 were found to have T-lymphocytopenia. The possibility has been raised that at least one of the cases may be associated with retroviral particles (1, 2). These developments have raised questions about the safety of the U.S. blood supply and current transfusion practices.While the uncertainty about the cause of the reported cases of idiopathic immunodeficiency is being resolved, physicians and patients must continue to make difficult decisions about transfusions. We need to be able to answer these questions: If the cause is infectious and the...References1. Unexplained CD4+ T-lymphocyte depletion in persons without evident HIV infection-United States. MMWR 1992;41:541-5. MedlineGoogle Scholar2. Update: CD4+ T-lymphocytopenia in persons without evident HIV infection-United States. MMWR. 1992;41:578-9. MedlineGoogle Scholar3. CummingWallaceSchorrDodd PEJR. Exposure of patients to human immunodeficiency virus through the transfusion of blood components that test antibody negative. N Engl J Med. 1989;321:941-6. CrossrefMedlineGoogle Scholar4. SurgenorWallaceHaoChapman DESR. Collection and transfusion of blood in the United States, 1982-1988. N Engl J Med. 1990;322:1646-51. CrossrefMedlineGoogle Scholar5. SilbersteinKruskallStehlingJohnstonRutmanSamia LMLMRC. Strategies for the review of transfusion practices. JAMA. 1989;262:1993-7. CrossrefMedlineGoogle Scholar6. . Perioperative red blood cell transfusion. Consensus Conference. JAMA. 1988;260:2700-3. CrossrefMedlineGoogle Scholar7. WelchMeehanGoodnough HKL. Prudent strategies for elective red blood cell transfusion. Ann Intern Med. 1992; 116:393-402. LinkGoogle Scholar8. Walker R. Special report: transfusion risks. Am J Clin Pathol. 1987;88:374-8. CrossrefMedlineGoogle Scholar9. Sazama K. Reports of 355 Transfusion-associated deaths: 1976 through 1985. Transfusion. 1990;30:583-90. CrossrefMedlineGoogle Scholar10. Myhre B. Fatalities from blood transfusion. JAMA. 1980;244:1333-5. CrossrefMedlineGoogle Scholar11. CohenMunozReitzNessFrazierYawn NABPOD. Transmission of retroviruses by transfusion of screened blood in patients undergoing cardiac surgery. N Engl J Med. 1989;320:1172-6. CrossrefMedlineGoogle Scholar12. DonahueNelsonMunozMcAllisterYawnNess JKAHDP. Transmission of HIV by transfusion of screened blood. N Engl J Med. 1990;323:1709. CrossrefMedlineGoogle Scholar13. NelsonDonahueMunozCohenNessTeague KJANPA. Transmission of retroviruses from seronegative donors by transfusion during cardiac surgery. A multicenter study of HIV-1 and HTLV-I/II infections. Ann Intern Med. 1992;117:554-9. LinkGoogle Scholar14. Iwarson S. Transfusion transmitted non-A, non-B hepatitis. Acta Anaesthesiol Scand. 1988;32(Suppl 89):13-5. CrossrefGoogle Scholar15. MosleyAachHollingerStevensBarbosaNemo JRFCLG. Non-A, non-B hepatitis and antibody to hepatitis C virus. JAMA. 1990;263:77-8. CrossrefMedlineGoogle Scholar16. KatkovDienstagCodyEvansChooHoughton WJHAQM. Role of hepatitis C in non-B chronic liver disease. Arch Intern Med. 1991;151:1548-52. CrossrefMedlineGoogle Scholar17. AachStevensHollingerMosleyPetersonTaylor RCFJDP. Hepatitis C virus infection in post-transfusion hepatitis. N Engl J Med. 1991;325:1325-9. CrossrefMedlineGoogle Scholar18. DonahueMunozNessBrownYawnMcAllister JAPDDH. The declining risk of post-transfusion hepatitis C virus infection. N Engl J Med. 1992;327:369-73. CrossrefMedlineGoogle Scholar19. WardHolmbergAllenCohnCritchleyKleinman JSJDSS. Transmission of human immunodeficiency virus (HIV) by blood transfusions screened as negative for HIV antibody. N Engl J Med. 1988;318:473-8. CrossrefMedlineGoogle Scholar20. Menitove J. The decreasing risk of transfusion-associated AIDS. N Engl J Med. 1989;321:966-8. CrossrefMedlineGoogle Scholar21. AlterPurcellShihMelpolderHoughtonChoo HRJJMQ. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med. 1989;321:1494-500. CrossrefMedlineGoogle Scholar22. van der PoelReesinkSchaasbergLeentvaar-KuypersBakkerExel-Oehlers CHWAEP. Infectivity of blood seropositive for hepatitis C virus antibodies. Lancet. 1990;335:558-60. CrossrefMedlineGoogle Scholar23. WeinsteinFinebergElsteinFrazierNeuhauserNeutra MHAHDR. Clinical Decision Analysis. Philadelphia: W.B. Saunders Co.; 1980. Google Scholar24. DoneganStuartNilandSacksAzenDietrich EMJHSS. Infection with human immunodeficiency virus type 1 (HIV-1) among recipients of antibody-positive blood donations. Ann Intern Med. 1990;113:733-9. LinkGoogle Scholar25. BerkelmanHeywardStehr-GreenCurran RWJJ. Epidemiology of human immunodeficiency virus infection and acquired immunodeficiency syndrome. Am J Med. 1989;86:761-70. CrossrefMedlineGoogle Scholar26. Dodd R. The risk of transfusion-transmitted infection. N Engl J Med. 1992;327:419-21. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIntraoperative salvage in patients undergoing elective abdominal aortic aneurysm repair: An analysis of cost and benefitOn the need for improved transfusion indicators in cardiac surgeryHIV Testing in Blood BanksReplyThe infectious risks of transfusions in the United States: A decision-analytic approachAcquired Immunodeficiency Syndrome 1 October 1992Volume 117, Issue 7Page: 612-614KeywordsBloodBlood transfusionHIVHealth care policyImmunodeficienciesInfectious diseasesPrevention, policy, and public healthSafety Issue Published: 1 October 1992 PDF downloadLoading ...

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 9 citations exist upstream.

References

1980Clinical Decision Analysis 1988Transmission of Human Immunodeficiency Virus (HIV) by Blood Transfusions Screened as Negative for HIV Antibody 1992The Risk of Transfusion-Transmitted Infection 1989Exposure of Patients to Human Immunodeficiency Virus through the Transfusion of Blood Components That Test Antibody-Negative 1990Collection and Transfusion of Blood in the United States, 1982–1988 1989Transmission of Retroviruses by Transfusion of Screened Blood in Patients Undergoing Cardiac Surgery 1992Transmission of Retroviruses from Seronegative Donors by Transfusion during Cardiac Surgery 1990Transmission of HIV by Transfusion of Screened Blood

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.