Nanoparticle‐Enhanced Fluorescence Imaging of Latent Fingerprints Reveals Drug Abuse

Otto S. Wolfbeis

82 citations0/0 files storedAngewandte Chemie International Edition

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Forensic Fingerprint Detection Methods Forensic Toxicology and Drug Analysis Biosensors and Analytical Detection

Abstract

No sweat! The sweat in a latent fingerprint (LFP) can contain orally ingested drugs and their metabolites. In a new method for drug detection, primary antibodies (Abs) against drug metabolites are conjugated to magnetic nanoparticles (NPs). The LFP is incubated with the NPs, excess particles removed, and the LFP treated with a fluorescently labeled secondary antibody. Fluorescence imaging then allows characterization.

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References

2001Advances in Fingerprint Technology 1977Criminalistics: An Introduction to Forensic Science 2007“Intelligent” Fingerprinting: Simultaneous Identification of Drug Metabolites and Individuals by Using Antibody‐Functionalized Nanoparticles 2008Metal-containing nanoparticles and nano-structured particles in fingermark detection 2008Imaging of Latent Fingerprints through the Detection of Drugs and Metabolites 2005The development of novel ninhydrin analogues 2003The detection of drugs of abuse in fingerprints using Raman spectroscopy I: latent fingerprints 2004The detection of drugs of abuse in fingerprints using Raman spectroscopy II: cyanoacrylate-fumed fingerprints

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2015Photoacoustic and Colorimetric Visualization of Latent Fingerprints 2016High-Resolution and Universal Visualization of Latent Fingerprints Based on Aptamer-Functionalized Core–Shell Nanoparticles with Embedded SERS Reporters 2016Recent progress on fingerprint visualization and analysis by imaging ridge residue components 2015Advances in the development and component recognition of latent fingerprints

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