Articlegold2012

Tailored vs. Standardized Internet-Based Cognitive Behavior Therapy for Depression and Comorbid Symptoms: A Randomized Controlled Trial

Robert Johansson · Elin Sjöberg · Per Carlbring · Andréas Rousseau · Gerhard Andersson

268 citations0/0 files storedPLoS ONE

No readable copy stored yet — this record is metadata only.

Digital Mental Health Interventions Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Mental Health Treatment and Access

Abstract

BACKGROUND AND AIMS: Major depression can be treated by means of cognitive behavior therapy, delivered via the Internet as guided self-help. Individually tailored guided self-help treatments have shown promising results in the treatment of anxiety disorders. This randomized controlled trial tested the efficacy of an Internet-based individually tailored guided self-help treatment which specifically targeted depression with comorbid symptoms. The treatment was compared both to standardized (non-tailored) Internet-based treatment and to an active control group in the form of a monitored online discussion group. Both guided self-help treatments were based on cognitive behavior therapy and lasted for 10 weeks. The discussion group consisted of weekly discussion themes related to depression and the treatment of depression. METHODS: A total of 121 participants with diagnosed major depressive disorder and with a range of comorbid symptoms were randomized to three groups. The tailored treatment consisted of a prescribed set of modules targeting depression as well as comorbid problems. The standardized treatment was a previously tested guided self-help program for depression. RESULTS: From pre-treatment to post-treatment, both treatment groups improved on measures of depression, anxiety and quality of life. The results were maintained at a 6-month follow-up. Subgroup analyses showed that the tailored treatment was more effective than the standardized treatment among participants with higher levels of depression at baseline and more comorbidity, both in terms of reduction of depressive symptoms and on recovery rates. In the subgroup with lower baseline scores of depression, few differences were seen between treatments and the discussion group. CONCLUSIONS: This study shows that tailored Internet-based treatment for depression is effective and that addressing comorbidity by tailoring may be one way of making guided self-help treatments more effective than standardized approaches in the treatment of more severe depression. TRIAL REGISTRATION: Clinicaltrials.gov NCT01181583.

Citations in this library

Stored only when both papers are in the corpus — 268 citations exist upstream.

References

1983A Global Measure of Perceived Stress 1988An inventory for measuring clinical anxiety: Psychometric properties.2009Introduction to Meta‐Analysis 2006Projections of Global Mortality and Burden of Disease from 2002 to 2030 2021Introduction to Meta‐Analysis 2001Validation of the Insomnia Severity Index as an outcome measure for insomnia research 1994Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study 2009The global burden of mental disorders: An update from the WHO World Mental Health (WMH) Surveys

Cited by

2014Blending online therapy into regular face-to-face therapy for depression: content, ratio and preconditions according to patients and therapists using a Delphi study 2016Features and functionality of the Iterapi platform for internet-based psychological treatment 2015Positive Imagery-Based Cognitive Bias Modification as a Web-Based Treatment Tool for Depressed Adults 2016A randomized controlled trial of the web-based OurRelationship program: Effects on relationship and individual functioning.2015Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial

Imported from OpenAlex (CC0) — nothing here is generated.