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Memory, Attention, Function, and Mood among Patients with Chronic Posttraumatic Stress Disorder

Neena Sachinvala · HAROLD von SCOTTI · Michael T. McGuire · Lynn A. Fairbanks · KELLY BAKST · Marsden H. McGuire +1 more

97 citations0/0 files storedThe Journal of Nervous and Mental Disease

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Posttraumatic Stress Disorder Research Traumatic Brain Injury Research Migration, Health and Trauma

Abstract

We report a study of memory, attention, function, and mood among 36 male Vietnam War Veterans suffering from chronic posttraumatic stress disorder (PTSD). PTSD subjects (N = 36) were in good physical health, suffering from moderate depression, and not knowingly suffering from other mental disorders. Control subjects (N = 18) were in good physical health, not knowingly suffering from a mental disorder, and matched with PTSD subject for age, sex, and level of education. Assessment instruments for PTSD subjects included the PostTraumatic Stress Diagnostic Scale (clinician administered), the Hamilton Depression Rating Scale (clinician administered), and the Cognitive Evaluation Protocol (CEP), a touchscreen computer assessment instrument that is self-administered by subjects. CEP was administered twice to PTSD subjects 1 month apart; other instruments were administered at the beginning of the study. Control subjects took CEP once and were administered the Hamilton Depression Rating Scale and the PostTraumatic Stress Diagnostic Scale once. Compared with control subjects, PTSD subjects performed significantly less well on CEP for the three cognitive domains of attention, memory, and function and had highly elevated depression scores. An interaction between depression and memory was found but not with depression and attention. There was no evidence of reduced information processing speed among PTSD subjects. Comparisons between the three assessment instruments showed a high degree of cross-assessment agreement. The findings are consistent with reports that chronic PTSD is associated with compromised memory, attention, and function. The study documents the feasibility of using self-administrated touchscreen computer programs to evaluate and track features of mental disorders.

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References

1960A RATING SCALE FOR DEPRESSION 1998Attention and memory dysfunction in posttraumatic stress disorder.1993Post-traumatic Stress Reactions in Children After the 1988 Armenian Earthquake 1995Autobiographical memory disturbance in combat-related posttraumatic stress disorder 1994Posttraumatic stress disorder in elderly and younger adults after the 1988 earthquake in Armenia 1995Learning and memory in combat veterans with posttraumatic stress disorder 1998Learning and Memory in Rape Victims With Posttraumatic Stress Disorder 1997Attentional bias in posttraumatic stress disorder

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