Can psychedelic compounds play a part in drug dependence therapy?

Ben Sessa · Matthew W. Johnson

57 citations0/0 files storedThe British Journal of Psychiatry

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Psychedelics and Drug Studies Substance Abuse Treatment and Outcomes Forensic Toxicology and Drug Analysis

Abstract

After a 40-year hiatus there is now a revisiting of psychedelic drug therapy throughout psychiatry, with studies examining the drugs psilocybin, ketamine, ibogaine and ayahuasca in the treatment of drug dependence. Limitations to these therapies are both clinical and legal, but the possibility of improving outcomes for patients with substance dependency imposes an obligation to research this area.

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References

1903The Varieties of Religious Experience.2011Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness 1997Ketamine Psychedelic Therapy (KPT): A Review of the Results of Ten Years of Research 2008Psychedelic Psychiatry 2012Therapeutic mechanisms of classic hallucinogens in the treatment of addictions: from indirect evidence to testable hypotheses 2014Hallucinogen use predicts reduced recidivism among substance-involved offenders under community corrections supervision 2008Psychedelic Psychiatry: LSD from Clinic to Campus 2012Shaping the renaissance of psychedelic research

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2019Ayahuasca: Uses, Phytochemical and Biological Activities 2019First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants 2021Associations between ayahuasca consumption in naturalistic settings and current alcohol and drug use: Results of a large international cross‐sectional survey

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