Turning a blind eye:Testing the success of blinding and the CONSORT statement

Douglas G. Altman · Kenneth F. Schulz · David Moher

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Meta-analysis and systematic reviews Statistical Methods in Clinical Trials Advanced Causal Inference Techniques

Abstract

EDITOR—Reports of randomised trials should state clearly whether blinding was attempted, and if so who was blinded and how this was done.1 Fergusson et al note that blinding may be ineffective in some trials, making them less sound methodologically than they seem to be.2 But trial participants asked to …

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References

2001The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials 2001The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration 2004Turning a blind eye: the success of blinding reported in a random sample of randomised, placebo controlled trials

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2008Extending the CONSORT Statement to Randomized Trials of Nonpharmacologic Treatment: Explanation and Elaboration 2005The Consolidated Standards of Reporting Trials (CONSORT)2010CONSORT 2010 changes and testing blindness in RCTs 2016Unreported formal assessment of unblinding occurred in 4 of 10 randomized clinical trials, unreported loss of blinding in 1 of 10 trials 2011Assessing blinding in randomised controlled trials of acupuncture: Challenges and recommendations 2010Reporting guidelines for primary research: Saying what you did 2010CONSORT 2010 and Controversies Regarding Assessment of Blindness in RCTs 2006Os dez mandamentos do ensaio clínico randomizado - princípios para avaliação crítica da literatura médica

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