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The model $E(y \mid x) = \theta_0 + \sum^k_{i=1} \theta_ix_i + \psi(\mathbf{x})$ is considered, where $\psi(\mathbf{x})$ is an unknown contamination with $| \psi(\mathbf{x})|$ bounded by given $\varphi(\mathbf{x})$. Optimal designs are studied in terms of least squares estimation and a family of minimax criteria. In particular, analogs of D-, A- and E-optimal designs are studied in the general case of an arbitrary $k$. Some commonly used integer designs are considered and their efficiencies with respect to optimal designs are determined. In particular, it is shown that star-point designs or regular replicas of $2^k$ factorials are very efficient under the appropriate choice of levels of factors.
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