The History of Blood Gases, Acids and Bases

Abstract

The History of Blood Gases, Acids and Basesby Drs Poul Astrup and John W. Severinghaus describes the development of methods of analyzing blood gases, acids, and bases from the time of Robert Boyle in the 17th century to the present. The major part of the book, written by Dr Astrup, covers events and discoveries up to 1950. Dr Severinghaus, in the final chapter, describes developments since 1950, emphasizing the work of Poul Astrup, who showed that with only a pH electrode he could measure blood Pco2and acid-base balance, which he later called "base excess"; Ole Siggaard-Andersen, who developed an important pH/log Pco2diagram; Leland Clark, who invented a platinum electrode to measure blood Po2; and Richard Stow, who invented the CO2electrode. The book has been written by authorities in the field. Dr. Astrup- has invented methods and equipment for simply measuring blood pH

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