Application of Factorial and Response Surface Methodology in Modern Experimental Design and Optimization

2006-12-01articleCritical Reviews in Analytical Chemistry315 citationsclosed

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Optimal Experimental Design Methods Spectroscopy and Chemometric Analyses Advanced Scientific Research Methods

Abstract

This article critically examines the use of factorial and response surface methodology in modern experimental design and optimization. A survey of important screening and optimization techniques in the literature since 2000 are presented. Current applications in biological, environmental and pharmaceutical analysis, food technology and industrial-related processes are examined.

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References

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1996Response Surface Methodology

2005Statistics and Chemometrics for Analytical Chemistry

1998Experimental design and optimization

1998Handbook of Chemometrics and Qualimetrics

2000The Theory of the Design of Experiments

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1989Experimental Design: A Chemometric Approach

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