Statistical Proof in Inconclusive 'Negative' Trials

JAMES F. REED

50 citations0/0 files storedArchives of Internal Medicine

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Meta-analysis and systematic reviews Statistical Methods in Clinical Trials Statistical Methods in Epidemiology

Abstract

Three hundred thirty-five published articles from six medical journals that contained "negative" results were examined to determine the probability of detecting "small," "medium," and "large" therapeutic improvements. The mean probability of detecting a small effect size was.138; for a medium effect size, the probability was.387; and for a large effect size, it was.614. (Arch Intern Med1981;141-1307-1310)

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1966Statistical Evaluation of Medical Journal Manuscripts 1972On the Power of Statistical Tests in the American Educational Research Journal

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