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This study addressed the use of the Millon Clinical Multiaxial Inventory-II (Millon-II) in assessing 73 substance abusers. The influence of neuropsychological functioning on personality functioning is discussed and evaluated. Reported history of substance abuse did not significantly relate to measures of neuropsychological or personality functioning. Of the sample, 16.9% produced invalid Million-II scores; invalidity was not significantly related to demographic characteristics or history of substance abuse. Millon-II profile validity was related to verbal and perceptual-motor functioning. Some neuropsychological variables significantly predicted Millon-II scale scores but with little consistency.
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