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Ecstasy induces apoptosis via 5-HT2A-receptor stimulation in cortical neurons · Study

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ArticleEcstasy induces apoptosis via 5-HT2A-receptor stimulation in cortical neurons

João Paulo Capela2007

Article2007

Ecstasy induces apoptosis via 5-HT2A-receptor stimulation in cortical neurons

João Paulo Capela · Eduarda G. R. Fernandes · Fernando Remião · Maria de Lourdes Bastos · Andreas Meisel · Félix Dias Carvalho

79 citations·0/0 files stored·NeuroToxicology

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Psychedelics and Drug Studies Neurotransmitter Receptor Influence on Behavior Forensic Toxicology and Drug Analysis

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References

2003The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)2004Hallucinogens 1998Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings 1987Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.1988Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites 2002The Acute and Chronic Effects of MDMA (“Ecstasy”) on Cortical 5-HT2A Receptors in Rat and Human Brain 1996Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.

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2006Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermiaarticle · 7 shared references 2009Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overviewreview · 5 shared references 2003Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanismsreview · 5 shared references 2006Ecstasy: Are animal data consistent between species and can they translate to humans?review · 5 shared references 2011In Vivo Imaging of Cerebral Serotonin Transporter and Serotonin2A Receptor Binding in 3,4-Methylenedioxymethamphetamine (MDMA or “Ecstasy”) and Hallucinogen Usersarticle · 5 shared references 2005Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [11C]McN5652 and [11C]DASBarticle · 4 shared references

Details

Year2007

Typearticle

Published2007-04-30

VenueNeuroToxicology

ISSN-L0161-813X

Languageen

Citations79

Files0 public / 0

ShelfPsychedelics and Drug Studies

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doi10.1016/j.neuro.2007.04.005

openalex_workW2058876115

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