Articlebronze2011

MSLT in Primary Insomnia: Stability and Relation to Nocturnal Sleep

Timothy Roehrs · Surilla Randall · Erica J. Harris · Renee Maan · Thomas G. Roth

84 citations0/0 files storedSLEEP

No readable copy stored yet — this record is metadata only.

No open-access location is known for this record yet.

Literature note Cite in a project Citation map

Abstract

MSLT Stability in Insomnia-Roehrs et alniacs and controls with mean daily sleep latencies of 10.3 vs 8.6 min.15 What is evident in the studies above reporting significant MSLT differences between insomniacs and controls are the differences among the studies in the control sample MSLT mean sleep latencies, which range from 8.6 min to 12.3 min.All these studies used samples of convenience, recruiting their control samples through newspaper advertisements for normal sleepers.To better understand whether the MSLT is elevated in insomniacs it would be valuable to compare insomniacs to a population-based, representative sample of healthy non-insomniacs.The studies of MSLT in insomnia also differ in the definition of insomnia used.Some of the above cited studies defined insomnia based on a single complaint only, others used the standard clinical diagnostic criteria, and others included nocturnal polysomnographic (NPSG) entry criteria.How nocturnal sleep time relates to MSLT in insomnia is an important theoretical question.In studies of healthy normals, short MSLT mean daily sleep latencies are associated with diary-reported short total sleep times and high laboratory sleep efficiencies the night before the MSLT.16 These results suggest that the less the habitual nocturnal sleep, the greater the degree of daytime sleepiness.The question arises as to how sleep time in insomniacs relates to their MSLTs the following day.Finally, the studies of MSLT in insomnia report relatively large standard deviations.The wide variability among insomniacs may reflect high test-retest variability in a given individual's MSLT.No study has assessed the repeatability of MSLT results in insomniacs across time.Will an insomniac with an elevated MSLT show the same elevation across time?In this paper, we report MSLT results of a large sample of insomniacs participating in a chronic pharmacological treatment trial; compare these results to a representative population control sample; evaluate the relation of MSLT to NPSG sleep time; and importantly, assess the stability of the MSLT in insomnia.

Paper brief

Loading…

Cite this work

Citation unavailable for this work.

BibTeX RIS CSL-JSON

No public copy is stored for this record, so only the metadata is cited.

Citations in this library

Citation map →

Stored only when both papers are in the corpus — 84 citations exist upstream.

References

1968A manual for standardized terminology, techniques and scoring system for sleep stages in human subjects 2001Chronic Insomnia Is Associated with Nyctohemeral Activation of the Hypothalamic-Pituitary-Adrenal Axis: Clinical Implications 2004Functional Neuroimaging Evidence for Hyperarousal in Insomnia 1982Sleeping and waking disorders : indications and techniques 199524-Hour Metabolic Rate in Insomniacs and Matched Normal Sleepers 2001Beta/Gamma EEG Activity in Patients with Primary and Secondary Insomnia and Good Sleeper Controls 1984Sleep Fragmentation and Daytime Sleepiness 1988Daytime Alertness in Patients with Chronic Insomnia Compared with Asymptomatic Control Subjects

Cited by

2015Sleep and Repetitive Thought 2013The Glasgow Sleep Impact Index (GSII): A novel patient-centred measure for assessing sleep-related quality of life impairment in Insomnia Disorder 2013Insomnia With Short Sleep Duration 2014Abnormal daytime sleepiness in dementia with Lewy bodies compared to Alzheimer’s disease using the Multiple Sleep Latency Test 2020Acute and Chronic Insomnia: What Has Time and/or Hyperarousal Got to Do with It?

Explore the map →

Papers that cite the same references — the relational fallback while embeddings are still backfilling.

Imported from OpenAlex (CC0) — nothing here is generated.