Working memory deficits in current and previous users of MDMA (‘ecstasy’)

Michelle Wareing · John E. Fisk · Philip N. Murphy

185 citations0/0 files storedBritish Journal of Psychology

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Psychedelics and Drug Studies Forensic Toxicology and Drug Analysis Cognitive Abilities and Testing

Abstract

Current and previous users of the drug MDMA ('ecstasy') were tested on measures of central executive functioning, information processing speed, and on self-report measures of arousal and anxiety. The results were compared with those for a control group who did not use MDMA. Relative to the control group, both user groups were found to be impaired in some aspects of central executive functioning. Also, there were significant group differences on the measures of anxiety (users were more anxious) and on arousal (previous users scoring higher on the arousal measure relative to current users). Users processed information as quickly as non-users but less accurately. Some possible mediators of the above group differences are discussed.

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1996Exploring the Central Executive

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2002Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") polydrug users 2006The confounding problem of polydrug use in recreational ecstasy/MDMA users: a brief overview 2001Ecstasy use: cognitive deficits related to dosage rather than self-reported problematic use of the drug 2002The health effects of ecstasy: a literature review 2003Memory impairment suggests hippocampal dysfunction in abstinent ecstasy users 2005“Partying” Hard: Party Style, Motives for and Effects of MDMA Use at Rave Parties 2006MDMA in humans: factors which affect the neuropsychobiological profiles of recreational ecstasy users, the integrative role of bioenergetic stress 2004Residual neuropsychological effects of illicit 3,4-methylenedioxymethamphetamine (MDMA) in individuals with minimal exposure to other drugs

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