Articlebronze2013

Midlife Sleep Characteristics Associated with Late Life Cognitive Function

Jyri J. Virta · Kauko V Heikkila · Markus Perola · Markku J. Koskenvuo · Ismo J. Räihä · Juha O. Rinne +1 more

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Abstract

STUDY OBJECTIVES: Previous studies with limited follow-up times have suggested that sleep-related traits are associated with an increased risk of incident dementia or cognitive decline. We investigated the association between midlife sleep characteristics and late life cognitive function. DESIGN: A follow-up study with a median follow-up time of 22.5 (range 15.8-25.7) years assessing the association between midlife sleep characteristics and later cognitive function. SETTING: Questionnaire data from 1981 were used in the assessment of sleep characteristics, use of hypnotics, and covariates at baseline. Between 1999 and 2007, participants were assigned a linear cognitive score with a maximum score of 51 based on a telephone interview (mean score 38.3, SD 6.1). Linear regression analyses were controlled for age, sex, education, ApoE genotype, and follow-up time. PARTICIPANTS: 2,336 members of the Finnish Twin cohort who were at least 65 years of age. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: Baseline short (< 7 h/day) and long (> 8 h/day) sleepers had lower cognitive scores than participants sleeping 7-8 h/ day (β = -0.84, P = 0.014 and β = -1.66, P < 0.001, respectively). As compared to good sleep quality, poor or rather poor sleep quality was associated with a lower cognitive score (β = -1.00, P = 0.011). Also, the use of hypnotics ≥ 60 days per year was associated with poorer cognitive function (β = -1.92, P = 0.002). CONCLUSIONS: This is the first study indicating that midlife sleep length, sleep quality, and use of hypnotics are associated with late life cognitive function. Further confirmation is needed, but sleep-related characteristics may emerge as new risk factors for cognitive impairment.

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References

2002Mortality Associated With Sleep Duration and Insomnia 2007Sleep and Mortality: A Population-Based 22-Year Follow-Up Study 2006Poor Sleep Is Associated With Impaired Cognitive Function in Older Women: The Study of Osteoporotic Fractures 2002Daytime Sleepiness and Cognitive Impairment in the Elderly Population 2001Daytime Sleepiness Is Associated with 3-Year Incident Dementia and Cognitive Decline in Older Japanese-American Men 2012Sleep Quality and 1-Year Incident Cognitive Impairment in Community-Dwelling Older Adults 2001Insufficient Sleep—A Population-Based Study in Adults 2010Sleep disorders in aging and dementia

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