Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration

Douglas G. Altman · Lisa M. McShane · Willi Sauerbrei · Sheila E. Taube

1,018 citations0/0 files storedPLoS Medicine

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Meta-analysis and systematic reviews Statistical Methods in Clinical Trials Statistical Methods in Epidemiology

Abstract

The REMARK (Reporting Recommendations for Tumor Marker Prognostic Studies) guideline includes a checklist which aims to improve the reporting of these types of studies. Here, we expand on the REMARK checklist to enhance its use and effectiveness through better understanding of the intent of each item and why the information is important to report. Each checklist item of the REMARK guideline is explained in detail and accompanied by published examples of good reporting. The paper provides a comprehensive overview to educate on good reporting and provide a valuable reference of issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general.

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References

2009The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration 2007The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies 2010CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials 2010CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials 2010CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials 2007Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration 2001The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration 2007Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration

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2009A catalogue of reporting guidelines for health research 2015Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): the TRIPOD Statement 2015Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD)

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