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Validation and variability: Dual challenges on the path from systems biology to systems medicine
16 references·6 citing·41 second hop
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References

  • 2007Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning7,214 cited
  • 1990The Normal and the Pathological1,595 cited
  • 1995The Advancement of Science780 cited
  • 2013Simulation and similarity: using models to understand the world630 cited
  • 1997The disunity of science: Boundaries, contexts, and power525 cited
  • 2002Making sense of life: explaining biological development with models, metaphors, and machines513 cited
  • 2005Extending ourselves: computational science, empiricism, and scientific method487 cited
  • 2002How Scientific Practices Matter: Reclaiming Philosophical Naturalism328 cited
  • 2008Does matter really matter? Computer simulations, experiments, and materiality239 cited
  • 2005Fundamental issues in systems biology237 cited
  • 2007Systems Biology: Philosophical Foundations226 cited
  • 2005Experiments versus models: New phenomena, inference and surprise212 cited
  • 2012Assessing the Reliability of Complex Models: Mathematical and Statistical Foundations of Verification, Validation, and Uncertainty Quantification185 cited
  • 2009Contemporary Debates in Philosophy of Biology176 cited
  • 2011Fictions in Science: Philosophical Essays on Modeling and Idealization

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170 cited
  • 2011Re-thinking organisms: The impact of databases on model organism biology165 cited
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    • 2017Rethinking correspondence: how the process of constructing models leads to discoveries and transfer in the bioengineering sciences15 cited
    • 2019Systems science and the art of interdisciplinary integration14 cited
    • 2017The Sum of the Parts: Large-Scale Modeling in Systems Biology14 cited
    • 2021The applicability of mathematics in computational systems biology and its experimental relations7 cited