Articlebronze2015

Granulomatous reaction to red tattoo pigment treated with allopurinol

Mariana Marteleto Godinho · Felipe Aguinaga · Rachel Grynszpan · Victor Maselli Lima · David Rubem Azulay · Tullia Cuzzi +2 more

41 citations0/0 files storedJournal of Cosmetic Dermatology

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Tattoo and Body Piercing Complications Sarcoidosis and Beryllium Toxicity Research Skin Diseases and Diabetes

Abstract

Granulomatous reactions to tattoo ink are most commonly associated with mercury sulfide, a component of red pigments. Treatment options show limited results. Allopurinol, an inhibitor of xanthine oxidase, has been reported as a successful alternative treatment to granulomatous disorders, such as sarcoidosis and granulomatous reactions to fillers and tattoos. We report a case of granulomatous reaction to red tattoo pigment treated with allopurinol for 6 months. Good clinical improvement could be noticed during this time. Two months after we stopped the treatment, the lesion recurred. Allopurinol emerges as an important drug for the management of granulomatous reactions caused by tattoo pigments. Based on the significant clinical improvement noticed during its use, we recommend new studies to elucidate all the potential benefits of the use of allopurinol for the treatment of granulomatous reactions to tattoo ink.

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References

2009Cutaneous allergic reactions to tattoo ink 2014Tattoo-Associated Skin Reaction: The Importance of an Early Diagnosis and Proper Treatment 1998A reaction to a red lip cosmetic tattoo 2012Acute complications of tattooing presenting in the ED

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2024Lessons learned in a decade: Medical‐toxicological view of tattooing 2020Ablative laser surgery for allergic tattoo reactions: a retrospective study 2019Tattoo-associated complications and related topics: A comprehensive review 2016Réactions dites « allergiques » aux tatouages : prise en charge et algorithme thérapeutique 2018Inflammatory Reactions to Red Tattoo Inks: Three cases highlighting an emerging problem 2019Late-onset pseudoepitheliomatous hyperplasia developing within a red ink tattoo 2023Pathogenesis, Diagnosis and Management of Squamous Cell Carcinoma and Pseudoepithelial Hyperplasia Secondary to Red Ink Tattoo: A Case Series and Review 2019Tattoo skin reaction treatment with topical allopurinol: a good alternative

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