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Pharmaceutical Innovation in the 21st Century: New Drug Approvals in the First Decade, 2000–2009

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References

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2007The cost of biopharmaceutical R&D: is biotech different?517 cited
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2016Changing R&D models in research-based pharmaceutical companies286 cited
2014Scientific and Regulatory Reasons for Delay and Denial of FDA Approval of Initial Applications for New Drugs, 2000-2012214 cited
2014An overview of FDA-approved new molecular entities: 1827–2013211 cited
2013Clinical Approval Success Rates for Investigational Cancer Drugs203 cited
2015Cardiovascular Drug Development202 cited
2016ecancermedicalscience173 cited
2013Models for open innovation in the pharmaceutical industry148 cited
2013An Improved Approach To Measuring Drug Innovation Finds Steady Rates Of First-In-Class Pharmaceuticals, 1987–2011138 cited
2020Trends in FDA drug approvals over last 2 decades: An observational study128 cited

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2015

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2012Innovation and Access to Medicines for Neglected Populations: Could a Treaty Address a Broken Pharmaceutical R&D System?112 cited

2019Do Mandatory Disclosure Requirements for Private Firms Increase the Propensity of Going Public?84 cited

2019Decision-support challenges in the chemical-pharmaceutical industry: Findings and future research directions78 cited

2015Clinical trial metadata: defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme75 cited

2013The current development of CNS drug research73 cited

2018Entangled Decisions: Knowledge Interdependencies and Terminations of Patented Inventions in the Pharmaceutical Industry49 cited