Article2010

Generic and Illness-Specific Quality of Life in Obsessive-Compulsive Disorder

Marit Hauschildt · Lena Jelinek · Sarah Randjbar · Birgit Hottenrott · Steffen Moritz

54 citations0/0 files storedBehavioural and Cognitive Psychotherapy

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Obsessive-Compulsive Spectrum Disorders Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Perfectionism, Procrastination, Anxiety Studies

Abstract

BACKGROUND: Obsessive compulsive disorder (OCD) is a chronic and disabling disorder. It profoundly compromises various aspects of patients' everyday life, thus affecting their quality of life (QoL). Using generic instruments, several studies have confirmed severely impaired health-related QoL in patients diagnosed with OCD. However, there has been a dearth of research on illness-specific QoL. AIMS: The present study aimed to further investigate subjective QoL in individuals with OCD with a focus on illness-specific aspects. METHOD: To assess subjective QoL in a broad OCD sample, an internet survey was conducted with 123 participants with obsessive-compulsive symptoms. The survey comprised both a generic (WHOQOL-BREF) and a novel self-developed OCD-specific QoL measure (QoLOC). Psychopathology was determined with diagnostic standard instruments (self-report forms of: Y-BOCS, OCI-R, BDI-SF). RESULTS: Regression analyses confirmed depression as the best predictor for decreased QoL. In addition, participants reported high despair resulting from OCD-related problems that differed across symptom subtypes. An exploratory factor analysis suggested four domains of OCD-specific problems tapped by the QoLOC: (1) depressiveness in association with OCD; (2) constraints in activities due to OCD symptoms or avoidance; (3) problems with partner and/or family due to OCD symptoms or avoidance; (4) self-concept/coping of own illness. CONCLUSIONS: Results produced a comprehensive picture of QoL impairments and their relation to psychopathology in a representative OCD sample. Illness-specific concerns should be further addressed in QoL research in OCD because such problems are not sufficiently mirrored in generic QoL measures.

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References

1992The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.1992The MOS 36-ltem Short-Form Health Survey (SF-36)1999Sample size in factor analysis.2004The World Health Organization's WHOQOL-BREF quality of life assessment: Psychometric properties and results of the international field trial. A Report from the WHOQOL Group 2002The Obsessive-Complusive Inventory: Development and validation of a short version.1988Relation of sample size to the stability of component patterns.1989The Yale-Brown Obsessive Compulsive Scale 2008Treatment gap in mental health care.

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2014Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders 2019Obsessive–compulsive disorder 2014Quality of life in children with OCD before and after treatment

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