Computerized geometric features of carpal bone for bone age estimation

Chi‐Wen Hsieh · Tai‐Lang Jong · Yi‐Hong Chou · Chui‐Mei Tiu

49 citations0/0 files storedChinese Medical Journal

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Forensic Anthropology and Bioarchaeology Studies Artificial Intelligence in Healthcare Medical Imaging and Analysis

Abstract

BACKGROUND: Bone age development is one of the significant indicators depicting the growth status of children. However, bone age assessment is an heuristic and tedious work for pediatricians. We developed a computerized bone age estimation system based on the analysis of geometric features of carpal bones. METHODS: The geometric features of carpals were extracted and analyzed to judge the bone age of children by computerized shape and area description. Four classifiers, linear, nearest neighbor, back-propagation neural network, and radial basis function neural network, were adopted to categorize bone age. Principal component and discriminate analyses were employed to improve assorting accuracy. RESULTS: The hand X-ray films of 465 boys and 444 girls served as our database. The features were extracted from carpal bone images, including shape, area, and sequence. The proposed normalization area ratio method was effective in bone age classification by simulation. Besides, features statistics showed similar results between the standard of the Greulich and Pyle atlas and our database. CONCLUSIONS: The bone area has a higher discriminating power to judge bone age. The ossification sequence of trapezium and trapezoid bones between Taiwanese and the atlas of the GP method is quite different. These results also indicate that carpal bone assessment with classification of neural networks can be correct and practical.

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References

1959RADIOGRAPHIC ATLAS OF SKELETAL DEVELOPMENT OF THE HAND AND WRIST 1976Assessment of Skeletal Maturity and Prediction of Adult Height (TW2 Method)2001Computer-assisted bone age assessment: image preprocessing and epiphyseal/metaphyseal ROI extraction 2001Skeletal Age Determinations in Children of European and African Descent: Applicability of the Greulich and Pyle Standards 1986Assessment of bone age: a comparison of the Greulich and Pyle, and the Tanner and Whitehouse methods 1993Feature extraction in carpal-bone analysis 2003Integration of computer assisted bone age assessment with clinical PACS

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