Gender differences in the relationship between religiosity and substance use (lifetime prevalence and current use) were examined among high school students in Szeged, Hungary (N = 881). Experimenting with and consuming tobacco and alcoholic beverages were characteristic in the sample to a great extent, whereas marijuana use was not as frequent. Logistic regression analyses were employed to test how variables of religiosity, that is, denominational affiliation, religiosity, and religious attendance, were related to substance use of youth by gender. Our findings confirmed the importance of the protective role of religious involvement, particularly among females.
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