Anemia in prospective blood donors deferred by the copper sulphate technique of hemoglobin estimation

Samuel S. Antwi-Baffour · David Annor Kwasie · Jonathan Kofi Adjei · Ransford Kyeremeh · George Kpentey · Foster Kyei

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Blood donation and transfusion practices Iron Metabolism and Disorders Blood transfusion and management

Abstract

BACKGROUND: Patients who require transfusion as part of their clinical management have the right to expect sufficient blood to be available to meet their needs and to receive the safest blood possible. Donor deferrals (disqualification) lead to loss of precious blood donors and blood units available for transfusion purposes. It is believed that a large majority of donor deferrals are due to temporal and correctable causes such as anemia in developing countries. It is therefore important to determine anemia among donor population to inform decision-making on the type of measures to be taken to reduce deferrals due to anemia. The aim of the study was to determine anemia in prospective blood donors deferred by the copper sulphate technique of hemoglobin estimation. This, to provide information that would help plan a future strategy for donor recruitment and management. METHODS: Three (3) ml of venous blood samples were collected from the study subjects into EDTA anticoagulant tubes. The hemoglobin levels and red cell indices were measured using Sysmex hematology analyser. A thin blood film was prepared and stained using Leishman stain and then observed under the light microscope. RESULTS: The prevalence of anemia among the total deferred patients (538) was 17.1 %. Four different types of anemia were found among the subjects. These were normocytic normochromic (46.74 %), microcytic hypochromic (42.39 %) normocytic hypochromic (8.70 %), and microcytic normochromic anemia (2.17 %). CONCLUSION: The study showed that a significant number of the prospective blood donors deferred for having low hemoglobin by the copper sulphate method turned out to have anemia by the standard method of diagnosis. Prevalence of anemia among apparently healthy blood donors was therefore higher than expected. Measures must therefore be taken to address this in order not to lose potential blood donors due to a correctable and preventable cause such as anemia.

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2007The consequences of temporary deferral on future whole blood donation 2010Towards 100% voluntary blood donation: a global framework for action.2010Pre-donation deferral of blood donors in South Indian set-up: An analysis 2007Whole blood donor deferral rate and characteristics of the Turkish population 2001Blood donor suitability and allogeneic whole blood donation 2008Blood pre-donation deferrals--a teaching hospital experience.2004Adjusting our management of female blood donors: the key to an adequate blood supply 2010Blood center practice and education for blood donors with anemia

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