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Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons
8 references·16 citing·36 second hop
Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons (2001)Effects of dose, sex, and long-term abste…Gender differences in the subjective effects of MDMA (2001)Gender differences in the sub…Reducedin vivobinding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users (1999)Reducedin vivobinding to the …Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings (1998)Positron emission tomographic…Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in Humans (1994)Serotonin Neurotoxicity after…Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations. (1992)Lasting effects of (+-)-3,4-m…(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates (1988)(+/-)3,4-Methylenedioxymetham…Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. (1987)Neurotoxicity of the psychede…Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. (1987)Biochemical and histological …Safety pharmacology of acute MDMA administration in healthy subjects (2017)Safety pharmacology of acute …Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[11C]DASB and structural brain imaging study (2010)Decreased cerebral cortical s…Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage? (2006)Neurotoxicity of methylenedio…Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users: the longitudinal perspective (2006)Mood, cognition and serotonin…Ecstasy: Are animal data consistent between species and can they translate to humans? (2006)Ecstasy: Are animal data cons…Cerebellar Volumes in Pediatric Maltreatment-Related Posttraumatic Stress Disorder (2006)Cerebellar Volumes in Pediatr…A review of acute effects of 3,4-methylenedioxymethamphetamine in healthy volunteers (2006)A review of acute effects of …Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [11C]McN5652 and [11C]DASB (2005)Quantitative PET Studies of t…Elevated Impulsivity and Impaired Decision-Making in Abstinent Ecstasy (MDMA) Users Compared to Polydrug and Drug-Naïve Controls (2005)Elevated Impulsivity and Impa…“Partying” Hard: Party Style, Motives for and Effects of MDMA Use at Rave Parties (2005)“Partying” Hard: Party Style,…Preliminary evidence of hippocampal dysfunction in adolescent MDMA (?ecstasy?) users: possible relationship to neurotoxic effects (2004)Preliminary evidence of hippo…Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function (2004)Acute and long-term effects o…A Voxel-Based PET Investigation of the Long-Term Effects of “Ecstasy” Consumption on Brain Serotonin Transporters (2004)A Voxel-Based PET Investigati…Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users (2003)Mood, cognition and serotonin…Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms (2003)Methylenedioxymethamphetamine…Altered states: the clinical effects of Ecstasy (2003)Altered states: the clinical …An inventory for assessing different kinds of hostility. (1957)Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior (1983)Cognitive performance in (±) 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users: a controlled study (1999)Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) (2000)Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity (2002)A revised version of the psychoticism scale (1985)Computerized assessment in neuropsychiatry using CANTAB: discussion paper. (1992)Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence? (2001)Differential effects of MDMA, cocaine, and cannabis use severity on distinctive components of the executive functions in polysubstance users: A multiple regression analysis (2004)Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy (2005)3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. (1987)3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans (1994)(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals (2000)Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview (2009)Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents (1984)Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action (1998)Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research (2001)MDMA enhances emotional empathy and prosocial behavior (2013)RETRACTED ARTICLE: MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials (2019)The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003)Neuroimaging of reward mechanisms in Gambling disorder: an integrative review (2018)Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data (1997)Developmental traumatology part II: brain development∗∗See accompanying Editorial, in this issue. (1999)Developmental traumatology: The psychobiological development of maltreated children and its implications for research, treatment, and policy (2001)Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus (2010)Reduced orbitofrontal and temporal grey matter in a community sample of maltreated children (2012)Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? (2013)Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits (1998)Cognitive performance amongst recreational users of "ecstasy" (2000)Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems (2001)Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug (1992)Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers (1998)Ecstasy (MDMA): a review of its possible persistent psychological effects (2000)Cardiovascular and Neuroendocrine Effects and Pharmacokinetics of 3,4-Methylenedioxymethamphetamine in Humans (1999)Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. (1988)Dose-Response Study of N,N-Dimethyltryptamine in Humans (1994)
this work references cited by second hop

References

  • 1998Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings658 cited
  • 1987Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.530 cited
  • 1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.453 cited
  • 2001Gender differences in the subjective effects of MDMA359 cited
  • 1994Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in Humans333 cited
  • 1988(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates300 cited
  • 1999Reducedin vivobinding to the serotonin transporter in the cerebral cortex of MDMA (‘ecstasy’) users280 cited
  • 1992Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.268 cited

Cited by

  • 2006Cerebellar Volumes in Pediatric Maltreatment-Related Posttraumatic Stress Disorder229 cited
  • 2005Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [11C]McN5652 and [11C]DASB204 cited
  • 2003Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms199 cited
  • 2003Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users190 cited
  • 2003

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Altered states: the clinical effects of Ecstasy
190 cited
  • 2006Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?189 cited
  • 2004A Voxel-Based PET Investigation of the Long-Term Effects of “Ecstasy” Consumption on Brain Serotonin Transporters183 cited
  • 2010Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[11C]DASB and structural brain imaging study172 cited
  • 2006Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users: the longitudinal perspective158 cited
  • 2004Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function153 cited
  • 2006A review of acute effects of 3,4-methylenedioxymethamphetamine in healthy volunteers149 cited
  • 2017Safety pharmacology of acute MDMA administration in healthy subjects146 cited
  • 2005“Partying” Hard: Party Style, Motives for and Effects of MDMA Use at Rave Parties144 cited
  • 2005Elevated Impulsivity and Impaired Decision-Making in Abstinent Ecstasy (MDMA) Users Compared to Polydrug and Drug-Naïve Controls127 cited
  • 2006Ecstasy: Are animal data consistent between species and can they translate to humans?126 cited
  • 2004Preliminary evidence of hippocampal dysfunction in adolescent MDMA (?ecstasy?) users: possible relationship to neurotoxic effects116 cited