Article2009

Insomnia in Japanese peri- and postmenopausal women

Masakazu Terauchi · Mihoko Akiyoshi · Kiyoko Kato · Eisuke Matsushima · T. Kubota

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Abstract

OBJECTIVE: To determine the prevalence and to identify the correlates of insomnia in Japanese peri- and postmenopausal women. METHOD: We retrospectively analyzed the records of 1451 peri- and postmenopausal women enrolled in the Systematic Health and Nutrition Education Program, conducted at the Menopause Clinic of the Tokyo Medical and Dental University Hospital, between 1995 and 2009. RESULTS: The prevalence of insomnia was 50.8%. The severity of insomnia correlated negatively with health-related quality of life (HR-QOL) scores on all the four domains assessed: physical health, mental health, life satisfaction and social involvement. With regard to other menopausal symptoms, insomnia correlated more strongly with depressed mood than with vasomotor symptoms, and one-third of insomniac women were seriously depressed. On categorizing the participants into four groups--not insomniac or depressed, N; insomniac but not depressed, I; not insomniac but depressed, D; insomniac and depressed, ID--the HR-QOL scores were observed to worsen in order N > I > D > ID. No significant difference was detected between groups I and ID with regard to their sleep quality measures. The number of heavy smokers was high in groups I and ID. With regard to the effect of the combination of medication and health/nutrition education, hormone therapy and nightly hypnotics significantly improved the insomnia symptoms, but hypnotics administered 'as needed' did not. CONCLUSIONS: Insomnia in Japanese peri- and postmenopausal women correlates more strongly with depressed mood than with vasomotor symptoms. Cessation of smoking may improve the women's sleep quality, and hormone therapy and nightly hypnotics are both effective treatments.

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References

2002Epidemiology of insomnia: what we know and what we still need to learn 1989Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?1989Epidemiologic Study of Sleep Disturbances and Psychiatric Disorders 2000An Epidemiological Study of Insomnia Among the Japanese General Population 2003Objective and Subjective Sleep Quality in Premenopausal, Perimenopausal, and Postmenopausal Women in the Wisconsin Sleep Cohort Study 1989SOCIAL NETWORK AND SOCIAL SUPPORT INFLUENCE MORTALITY IN ELDERLY MEN 2006Eszopiclone in Patients With Insomnia During Perimenopause and Early Postmenopause 2005Chronic Insomnia

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2018The effect of sleep hygiene education and relaxation exercises on insomnia among postmenopausal women: A randomized clinical trial 2014Treatment of Insomnia, Insomnia Symptoms, and Obstructive Sleep Apnea During and After Menopause: Therapeutic Approaches

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