Do eating disorders and affective disorders share a common etiology? A dissenting opinion

Abstract

Recent observations bringing into relationship the clinical phenomenology, family-genetic and biologic correlates, course and outcome, and epidemiology of eating disorders and affective disorders are examined. In all areas available evidence points to greater divergence than overlap between these disorders, arguing against the hypothesis that they share a common etiology. On this basis it is concluded that, although depression plays an important part in predisposing to eating disorders, continued attention must be paid to investigating mechanisms of etiology and pathogenesis unique to these conditions.

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