Pharmacologic treatment of binge eating disorder

William P. Carter · James I. Hudson · Justine K. Lalonde · Lindsay J. Pindyck · Susan L. McElroy · Harrison Graham Pope

145 citations0/0 files storedInternational Journal of Eating Disorders

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Eating Disorders and Behaviors Nutrition, Health and Food Behavior Pharmacology and Obesity Treatment

Abstract

OBJECTIVE: To review the findings from pharmacologic trials of binge eating disorder (BED) and to provide guidelines for pharmacologic treatment. METHODS: The literature was searched for studies of pharmacologic treatment of BED and related conditions, such as nonpurging bulimia nervosa. RESULTS: Placebo-controlled studies of desipramine, fluvoxamine, fluoxetine, sertraline, citalopram, dexfenfluramine, sibutramine, and topiramate have demonstrated the efficacy of these agents in the treatment of BED. An open trial of venlafaxine has offered preliminary evidence for the efficacy of this medication. Guidelines for pharmacologic management of BED are provided. CONCLUSIONS: The literature offers support for the use of agents from three categories of medication (antidepressants, appetite suppressants, and anticonvulsants) in the treatment of BED.

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References

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2007Efficacy of Sibutramine for the Treatment of Binge Eating Disorder: A Randomized Multicenter Placebo-Controlled Double-Blind Study 2005Toward an understanding of risk factors for binge-eating disorder in black and white women: a community-based case-control study 2013Perplexities of treatment resistence in eating disorders 2011Evidence-based pharmacotherapy of eating disorders 2011A double-blind, placebo-controlled trial of topiramate for pathological gambling

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