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A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration

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References

19873,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.458 cited
1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.453 cited
1986Effects of enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices307 cited
1992Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.268 cited
1987Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat183 cited
1988Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine.179 cited
1996Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.147 cited
1998In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain145 cited
1990Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors131 cited
1995Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing128 cited

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2001A study of the effect of a single neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") on the subsequent long-term behaviour of rats in the plus maze and open field

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92 cited

2005Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat79 cited

2008Tolerance to 3,4-methylenedioxymethamphetamine in rats exposed to single high-dose binges77 cited