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Today we can observe the formation of a new development model - knowledge economy. The knowledge economy development provides getting long-term competitive strengths. That's why it is important to detect factors which influence the structural changes in economic system. These factors can be both country- and region-specified. The authors suggest the hypothesis that the main factor which influences knowledge economy is the maturity of educational system. This hypothesis was confirmed on the basis of structural and mathematical modelling (basing on the materials of regions of Central Federal District of Russia). There were suggested measures on educational system development, aimed at stimulation of the knowledge economy formation.
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