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The microscope, such an integral part of pathology today, was only reluctantly accepted by physicians at the time of its invention in 1590. After the Dutch Zacharias Janssen invented the compound microscope by combining convex lenses in a tube, Holland and Italy became centers for the production and use of the new instrument. The name “microscope” was first suggested in 1625 by Faber a botanist. Early users of the microscope in Italy included: Galileo, an astronomer and physicist, Stelluti, a naturalist, Fontana, an astronomer, Faber, a botanists, Spallanzani, a biologist, Kirche, a Jesuit priest, and two physicians, Borelli and Malpighi [1].
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