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The unified psychotherapy movement proposes that the field develop holistic metatheories that embody multiple domains of clinical science (e.g., personality psychology, developmental psychopathology, psychotherapy research). Viewed by some as the next phase in the evolution of psychotherapy theory, practice, research, and integration, unified clinical science approaches are beginning to gain traction. In the current article, we propose context-responsive psychotherapy integration as one such approach. Context-responsiveness proposes an if-then structure for ther apists to respond to patients’ personal characteristics and emerging clinical scenar ios with context-relevant, evidence -based therapeutic strategies. This framework draws on both theory-specific and common treatment factors in response to salient markers that require responsive intervention on the therapist’s part. After outlining the context-responsive framework, we use the treatment of generalized anxiety dis order as an exemplar. We also discuss research strategies for supporting this frame work, as well as for supporting unified clinical science and psychotherapeutics as a whole. We view methodological pluralism and the bidirectionality between basic and applied research as key elements of the road to unification.
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